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Longstanding

In half a million UK adults, each 5 kg of lower grip went with 16–20% higher mortality

Grip strength and mortality in UK Biobank

The finding

Per 5 kg lower grip, the hazard ratio for all-cause mortality was 1.20 (1.17–1.23) in women and 1.16 (1.15–1.17) in men.

Authors
Celis-Morales CA, Welsh P, Lyall DM, et al.
Published
BMJ 361:k1651 · 2018
Evidence
Read in the primary source; numbers checked.
Source
doi.org/10.1136/bmj.k1651

How it was studied

Prospective cohort of 502,293 adults aged 40–69 (54% women). Mean follow-up 7.1 years; 13,322 deaths.

The numbers

Women and men respectively: cardiovascular mortality 1.19 (1.13–1.25) and 1.22 (1.18–1.26); respiratory mortality 1.31 (1.22–1.40) and 1.24 (1.20–1.28); all cancer 1.17 (1.13–1.21) and 1.10 (1.07–1.13).

The study defined weakness as grip under 26 kg in men and under 16 kg in women. Adding grip to an office-based risk score raised the C index by 0.013 for all-cause and 0.012 for cardiovascular mortality, a small improvement in prediction.

What it does not show

The authors say reverse causation and residual confounding cannot be excluded. UK Biobank volunteers are healthier than the general population.

What Longstanding does with it

This is why grip is in the battery. The small gain in the C index is also why the app does not turn your grip into a risk score: it adds a little to prediction for a population, and says much less about one person.

Tests this bears on

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